Volume 19, Issue 76 (9-2025)                   etiadpajohi 2025, 19(76): 181-198 | Back to browse issues page

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Afshar R, Mirnasuri R, Rahmati M. The Effect of 8 Weeks of Resistance Training on Serum Levels of Irisin and Brain-Derived Neurotrophic Factor in Substance-Dependent Women after Addiction Withdrawal. etiadpajohi 2025; 19 (76) :181-198
URL: http://etiadpajohi.ir/article-1-3266-en.html
Associate Professor, Department of Physical Education and Sports Sciences, Lorestan University, Khorramabad, Iran
Abstract:   (18 Views)
Objective: Given the role of substances in brain injury, this study investigated the effect of 8 weeks of resistance training on serum irisin and brain-derived neurotrophic factor (BDNF) in substance-dependent women after addiction withdrawal. Methods: This study was a quasi-experimental study with a pretest-posttest design and a control group. The study's statistical population comprised all women who attended NA centers in Khorramabad and had been free from traditional and industrial substance addiction for at least three months. From this population, 20 substance-dependent women after addiction withdrawal were purposefully selected and randomly assigned to an experimental group (resistance training group) (n=10) and a control group (n=10). The experimental group performed resistance training three sessions per week for 8 weeks, while the control group received no intervention. Blood samples were collected to measure irisin and BDNF. The data were analyzed using paired t-tests and analysis of covariance (ANCOVA). Results: The results showed that resistance training significantly increased the serum concentrations of irisin and BDNF in the experimental group subjects compared to the control group. Conclusion: Resistance training can be considered a low-cost and feasible intervention in the rehabilitation programs for substance-dependent women after addiction withdrawal.
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Type of Study: Research | Subject: General
Received: 2025/02/11 | Accepted: 2025/10/8 | Published: 2025/10/30

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