Objective: Addiction and the environment are important in developmental plans. NGOs play some part in the process of sustainable development. Drug reduction activities have recently assumed importance in the context of environmental protection and education through NGOs. Public participation plays a key role in the development of entrepreneurship in the field of the environment and prevention of the spread of drugs. Method: The research is a qualitative study. Semi-structured interviews were conducted in the statistical population, including experts, specialists, and managers of NGOs. Analysis in the qualitative section was performed using open and axial coding in three steps. Results: In this regard, 80 sub-factors and 11 core factors were identified, which are as follows: goals, managerial capabilities, culture, resources, educational maturity level, processes, relationships with external networks, structure, organizational strategies, knowledge management, and teaching methods. Conclusion: The identification of organizational factors improves the operational processes and optimizes the effectiveness of training and education.