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Arak University
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Abstract
Objective: Considering the destructive effects of drug use on liver function and blood lipid profile, this study aimed to investigate the effect of a period of aerobic exercise on liver function indices and blood lipid profile in men recovering from drug addiction.
Method: This quasi-experimental study was conducted with a pre-test-post-test design and controlled with a control group. The statistical population of this study consisted of men recovering from drug addiction who were kept in centers under the supervision of the Arak Welfare Organization in 1404. After announcing the call and conducting initial screening, 20 people (age: 35.4 ± 3.43) and eligible individuals who were willing to cooperate in the research were included in the present study in an accessible and purposeful manner. Then, the subjects were randomly divided into two aerobic exercise groups (10 people) and a control group (10 people). The exercise group performed 3 aerobic exercise sessions per week for 8 weeks at an intensity of 60-75% of maximum heart rate and a duration of 80 minutes per session, while the control group did not undergo any exercise intervention. Blood samples were taken from the subjects before and 48 hours after the intervention to measure liver enzymes (photometric method) and blood lipid profile (enzymatic). The data were analyzed using SPSS version 26 software and analysis of covariance with pre-test values as covariate. Results: The results of analysis of covariance with pre-test values as the covariate showed that eight weeks of aerobic exercise significantly improved blood lipid profile indicators (triglycerides, total cholesterol, LDL and HDL) in men recovering from addiction (P<0.05). Also, liver enzyme levels (Aspartate aminotransferase- Alanine aminotransferase- Alkaline phosphatase) decreased significantly after a training period in the exercise group (P<0.05), while no significant change was observed in the control group (P>0.05). Conclusion: A 2-month period of aerobic exercise is associated with improved metabolic status in men recovering from addiction, and it is suggested that exercise programs be considered as a low-cost and feasible method in rehabilitation programs for men recovering from addiction.
     
Type of Study: Research | Subject: General
Received: 2026/04/27 | Accepted: 2026/11/11

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