Objective: The present study compares the effectiveness of schema therapy and mindfulness on psychosomatic symptoms and its dimensions (somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid and psychotic) in patients with substance abuse stimulus. Methods: This quasi-experimental with pre-test and post-test and control groups took advantage of a three-month follow-up period. a control group were placed. treatment plan. mindfulness-hour experimental group in 8 sessions of 45 minutes were treated as a group. The participants in the General Health Questionnaire SCL90, before the start of the treatment, therapy sessions and follow-up stage groups were evaluated 3 months after treatment. The control group had no treatment group. Results: Using analysis of variance with repeated measures and ANCOVA results showed that the use of Schema Therapy and Mindfulness is effective in preventing relapse triggers. Conclusion: Both methods because shared components -Tny therapy in reducing symptoms of mental stimulant use was effective. Both encapsulation are also significant differences. And group schema therapy had a greater impact of mindfulness.